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TABLE 1. Mean differences (range) in cortical thickness due to variation in kernel size [voxels], computed as an average across all four specimens. ‘↓/↑’ denote a general reduction/increase in cortical thickness, respectively.

Parameter

Base

Shaft

Head

Overall

Closing kernel

 

 

 

 

-1

7.8% ↓ (2.1-12.2)

3.7% ↓ (0.2-7.0)

9.2% ↓ (2.5-15.6)

4.3% ↓ (0.5-8.1)

+1

9.3% ↑ (2.5-22.5)

3.0% ↑ (0.3-5.3)

8.3% ↑ (2.7-14.8)

3.6% ↑ (0.7-6.8)

Outer kernel

 

 

 

 

-1

0.0% ↓ (0.0-0.1)

0.0% ↓ (0.0-0.1)

0.1% ↓ (0.1-0.2)

0.1% ↓ (0.0-0.1)

+1

0.2% ↑ (0.1-0.4)

0.2% ↑ (0.1-0.3)

0.3% ↑ (0.2-0.3)

0.2% ↑ (0.1-0.3)

Inner kernel

 

 

 

 

-2

4.0% ↓ (3.6-4.6)

1.2% ↓ (0.5-1.8)

4.0% ↓ (1.7-6.4)

2.4% ↓ (1.5-3.2)

+2

1.9% ↑ (0.1-5.4)

0.6% ↑ (0.2-1.2)

1.7% ↑ (0.2-4.0)

0.8% ↑ (0.3-1.2)

TABLE 2. Mean relative changes in BV/TV and difference in angle of maximum trabecular orientation in degrees due to variation of grid distance, sampling sphere and mesh density (averaged over top and bottom region and over all 4 specimens). ‘↓/↑’ denote a reduction/increase in BV/TV. * Pongo specimen excluded due to size mismatch.

Parameter

Relative BV/TV difference:

Trabecular orientation

Grid Distance

 

 

+50%

3.1% ↓ (0.5-6.5)

0.8 (0.02-2.68)

+100%*

4.8% ↓ (0.2-10.5)

2.0 (0.06-4.64)

Sample Sphere

 

 

+50%

2.1% ↓ (0.2-5.2)

0.6 (0.09-1.36)

+100%

3.1% ↓ (1.1-6.2)

0.7 (0.13-1.42)

Mesh Density

 

 

-50%

2.3% ↑ (1.1-4.2)

0.5 (0.05-1.74)

+50%

2.1% ↓ (0.9-3.7)

0.3 (0.03-0.69)

TABLE 3. Morphological results from the standard parameter analysis measuring cortical thickness, bone volume fraction (BV/TV), major trabecular orientation (Trab. orientation) in the dorsopalmar plane relative to the proximodistal axis, degree of anisotropy (DA) and trabecular thickness (Tb. Th.) for each metacarpal specimen.

Parameter

Gorilla

Homo

Pan

Pongo

Cortical thickness

 

 

 

 

Base

1.29mm

0.30mm

1.53mm

0.78mm

Shaft

2.40mm

0.74mm

2.33mm

1.54mm

Head

1.84mm

0.38mm

1.31mm

0.68mm

Overall

2.00mm

0.59mm

1.87mm

1.18mm

BV/TV

 

 

 

 

Base

0.28

0.17

0.17

0.20

Shaft

0.20

0.08

0.06

0.131

Head

0.37

0.19

0.23

0.23

Trab. Orientation

 

 

 

 

Base

10.6

3.3

15.2

13.3

Head

1.9

11.8

1.5

-0.7

DA

 

 

 

 

Base

1.4

1.6

1.3

1.4

Head

1.1

1.6

1.2

1.4

Tb. Th.

 

 

 

 

Base

0.23mm

0.14mm

0.17mm

0.27mm

Head

0.28mm

0.16mm

0.22mm

0.27mm